Bisphosphonates explained

Feb. 18, 2010
A new iatrogenic plague is upon us — the wonders of science have succeeded in treating a condition, only to inflict us with an even worse one. Drs. Howard Kirschner and Austin Kirschner explain Bisphosphonates and their complications.

By Howard J. Kirschner, DDS, and Austin N. Kirschner, MD, PhD

A new iatrogenic plague is upon us. The wonders of science have succeeded in treating a condition, only to inflict us with an even worse one.

The magic of Bisphosphonates, used in the treatment of osteoporosis (bone loss), renders these patients susceptible to osteonecrosis of the jaw, and widespread osteomyelitis. The ADA reports that the risk is greater in cancer patients on intravenous Bisphosphonate therapy than the risk for patients on oral Bisphosphonate therapy.

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This article appeared in the Fall 2009 issue of NYSAGD (New York State Academy of General Dentistry) journal, GP, and is reprinted with permission. Visit www.nysagd.org for more information.