Researchers report promising plant-made antimicrobial peptide (PMAMP) for topical, low-cost disruption of oral biofilm

The protein drug rapidly killed Streptococcus mutans and impaired biofilm formation with a single application.

Nov. 14, 2016

Content Dam Diq En Articles Apex360 2016 11 Researchers Report Promising Plant Made Antimicrobial Peptide Pmamp For Topical Low Cost Disruption Of Oral Biofilm Leftcolumn Article Thumbnailimage File

In the October issue of Biomaterials, researchers at the University of Pennsylvania School of Dental Medicine published findings on a low-cost protein drug that holds promise for caries control. The topical drug utilizes two plant-made antimicrobial peptides (PMAMPs), retrocyclin and protegrin, along with a novel delivery system to control biofilm and quickly neutralize Streptococcus mutans.