New indicator may help identify patients with increased risk from throat cancer

Independent of other factors, such as smoking history and HPV status, matted lymph nodes appear to signal increased chance of oropharyngeal cancer spreading to other parts of the body, according to an article in ScienceDaily.

Researchers at the University of Michigan Health System have found a new indicator that may predict which patients with a common type of throat cancer are most likely have the cancer spread to other parts of their bodies.

Patients with oropharyngeal squamous cell carcinoma who had "matted" lymph nodes — nodes that are connected together — had a 69% survival rate over three years, compared to 94% for patients without matted nodes, according to a study published online ahead of print publication in Head & Neck.

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